Formulating a Skincare Product with Lyophilized (Freeze-Dried) Placenta Stem Cells & MCT Coconut Oil
Discover the power of regenerative skincare with our innovative formulations using lyophilized placenta stem cells and MCT coconut oil.
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Serum Formulation
Ingredients (for 30ml bottle):
  • Lyophilized Placenta Stem Cells – 100-300 mg
  • MCT Coconut Oil – 15 ml
  • Squalane (from olives) – 5 ml
  • Hyaluronic Acid (Low Molecular Weight) – 1 ml
  • Vitamin E (Tocopherol) – 0.5 ml
  • Coenzyme Q10 – 1 ml
  • Essential Oils (optional) – 0.5 ml
  • Preservative – 0.5 ml
Instructions:
  1. Rehydrate the lyophilized placenta stem cells in sterile water or saline solution.
  1. Mix MCT oil, squalane, vitamin E, and CoQ10 in a sterilized container.
  1. Add the rehydrated placenta stem cells to the oil mixture and blend using an emulsifier.
  1. If adding hyaluronic acid, mix it with a small portion of water before adding to the main formulation.
  1. Store in an airtight, dark glass dropper bottle to prevent oxidation.
Lotion Formulation

1

Ingredients (for 100 ml):
Lyophilized Placenta Stem Cells – 300 mg, MCT Coconut Oil – 15 ml, Shea Butter or Mango Butter – 10 ml, Emulsifying Wax – 5 ml, Aloe Vera Gel – 30 ml, Hyaluronic Acid – 2 ml, Niacinamide – 2 ml, Preservative – 0.5 ml, Distilled Water or Rose Hydrosol – 35 ml

2

Instructions:
1. Heat MCT oil, shea butter, and emulsifying wax in a double boiler. 2. Heat aloe vera gel and distilled water separately. 3. Slowly add water phase to oil phase while blending. 4. Add rehydrated placenta stem cells and mix well. 5. Add niacinamide, hyaluronic acid, and preservative, then stir until smooth. 6. Store in an airless pump bottle.
Effectiveness & Safety
Effectiveness
Placenta Stem Cells: Known for their regenerative properties, placenta-derived stem cells contain growth factors like EGF, TGF-β, and FGF, which promote collagen production, wound healing, and anti-aging benefits.
MCT Coconut Oil
Lightweight, non-comedogenic, and antimicrobial, making it suitable for all skin types.
Hyaluronic Acid & Niacinamide
Proven hydrating and brightening agents that work well in combination with growth factors.
Safety Considerations
  • Sterility: The rehydration process must be done in sterile conditions to prevent contamination.
  • Preservation: Since the serum is mostly oil-based, it has a longer shelf life, but any water-based ingredients in the lotion require a broad-spectrum preservative.
  • Allergies: Some individuals may have sensitivities to placenta-derived ingredients. Patch testing is recommended.
  • Regulatory Compliance: The source of placenta stem cells must be verified to ensure ethical and legal compliance.
Legal Considerations
United States (FDA)
Placenta-derived ingredients in cosmetics are not outright banned but must be properly processed and sourced from FDA-compliant suppliers. The product cannot make medical claims unless backed by clinical trials and registered as a drug. Proper labeling must indicate that it is for cosmetic use only.
Europe (EU Regulations)
Requires compliance with EU Cosmetic Regulation 1223/2009, including ingredient safety assessments and documentation. The Novel Ingredient Status may require additional testing for placenta-based products.
Asia
Some countries ban human-derived ingredients in cosmetics (e.g., China) but allow animal-derived placenta. South Korea and Japan have a history of using placenta-based skincare, but certification is required.
Additional Ingredients to Enhance the Product

1

1

Peptides
e.g., Matrixyl 3000 – Stimulates collagen and enhances skin repair.

2

2

Bakuchiol
A natural retinol alternative with anti-aging benefits.

3

3

Licorice Extract
Skin brightening and anti-inflammatory.

4

4

Resveratrol
Antioxidant that protects against environmental damage.

5

5

CBD or CBG
Anti-inflammatory and calming for the skin.
Astaxanthin – Strong antioxidant for UV protection.
Product Pricing
Why Increase the Price?

1

Luxury Positioning
Placenta-derived stem cell skincare is already a high-end market segment. Raising the price aligns with premium branding and exclusivity.

2

High Perceived Value
Competitor products using growth factors and stem cells (e.g., Augustinus Bader, La Mer, and MBR Skincare) retail for $250 - $400 per unit.

3

Premium Packaging
To justify a higher price, use high-end packaging (e.g., UV-protected glass bottles, gold accents, airless dispensers).

4

Clinical Testing & Marketing
If you invest in clinical testing, you can further differentiate the product and justify premium pricing.